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pentobarbital will reduce the extent or outcome of phenytoin by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.pentobarbital increases levels of vortioxetine by expanding metabolism. Modify Therapy/Watch Intently. Look at raising the vortioxetine dose when coadministered with sturdy CYP inducers for >14 times; not to e